Founded in 1949, QYH Biotech Co., Ltd. Zhengzhou Biopharmaceutical Factory(hereinafter referred to as Zhengzhou Factory) was founded in Kaifeng and moved to Zhengzhou in 1963. It was former one of the four major veterinary biological products manufacturers of the Ministry of Agriculture, and the earliest industrialized avian influenza vaccine manufacturer in China and one of the earliest designated manufacturers of high-pathogenic avian influenza vaccines by the Ministry of Agriculture. In July 2004, after the asset reorganization, it was renamed as QYH Biotech Co., Ltd. Zhengzhou Biopharmaceutical Factory, which is the inactivated vaccine production base of QYH Biotech Co., Ltd..